Gene: RAD51C ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587782528
rs587782528
RAD51C ; TEX14
T 0.700 CausalMutation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251

2015
dbSNP: rs730881942
rs730881942
RAD51C ; TEX14
C 0.700 CausalMutation CLINVAR Screening of Finnish RAD51C founder mutations in prostate and colorectal cancer patients. 23176254

2012
dbSNP: rs730881942
rs730881942
RAD51C ; TEX14
C 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs730881942
rs730881942
RAD51C ; TEX14
C 0.700 CausalMutation CLINVAR Genetic testing for RAD51C mutations: in the clinic and community. 25470109

2015
dbSNP: rs730881942
rs730881942
RAD51C ; TEX14
C 0.700 CausalMutation CLINVAR Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer. 27433846

2016
dbSNP: rs730881942
rs730881942
RAD51C ; TEX14
C 0.700 CausalMutation CLINVAR RAD51C is a susceptibility gene for ovarian cancer. 21616938

2011
dbSNP: rs757128712
rs757128712
RAD51C ; TEX14
T 0.700 CausalMutation CLINVAR Genetic testing for RAD51C mutations: in the clinic and community. 25470109

2015
dbSNP: rs757128712
rs757128712
RAD51C ; TEX14
A 0.700 GeneticVariation CLINVAR Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964

2010
dbSNP: rs757128712
rs757128712
RAD51C ; TEX14
T 0.700 CausalMutation CLINVAR Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964

2010
dbSNP: rs757128712
rs757128712
RAD51C ; TEX14
T 0.700 CausalMutation CLINVAR Pathological features of breast and ovarian cancers in RAD51C germline mutation carriers. 24993905

2014
dbSNP: rs1555603056
rs1555603056
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR

dbSNP: rs1555605074
rs1555605074
RAD51C ; LOC105371843
T 0.700 GeneticVariation CLINVAR Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. 27616075

2017
dbSNP: rs1555605103
rs1555605103
RAD51C ; LOC105371843
T 0.700 GeneticVariation CLINVAR Regulation of nonsense-mediated mRNA decay: implications for physiology and disease. 23500037

2013
dbSNP: rs1555605103
rs1555605103
RAD51C ; LOC105371843
T 0.700 GeneticVariation CLINVAR UniProt Knowledgebase: a hub of integrated protein data. 21447597

2011
dbSNP: rs587781287
rs587781287
RAD51C ; LOC105371843
T 0.700 CausalMutation CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716

2012
dbSNP: rs587781287
rs587781287
RAD51C ; LOC105371843
T 0.700 CausalMutation CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441

2015
dbSNP: rs587781287
rs587781287
RAD51C ; LOC105371843
T 0.700 CausalMutation CLINVAR Inherited Mutations in Women With Ovarian Carcinoma. 26720728

2016
dbSNP: rs587781287
rs587781287
RAD51C ; LOC105371843
T 0.700 CausalMutation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251

2015
dbSNP: rs587781410
rs587781410
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer. 28905878

2017
dbSNP: rs587781410
rs587781410
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Germline mutation in the RAD51B gene confers predisposition to breast cancer. 24139550

2013
dbSNP: rs587781410
rs587781410
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic. 26057125

2015
dbSNP: rs587781410
rs587781410
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Conflicting Interpretation of Genetic Variants and Cancer Risk by Commercial Laboratories as Assessed by the Prospective Registry of Multiplex Testing. 27621404

2016
dbSNP: rs587781410
rs587781410
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716

2012
dbSNP: rs587781410
rs587781410
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. 27616075

2017
dbSNP: rs587781995
rs587781995
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients. 26822949

2016